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Gene Expression Data
Assay Details
Assay
Reference: J:295033 Xu Q, et al., Autism-associated CHD8 deficiency impairs axon development and migration of cortical neurons. Mol Autism. 2018;9:65
Assay type: RNA in situ
MGI Accession ID: MGI:6477613
Gene symbol: Chd8
Gene name: chromodomain helicase DNA binding protein 8
Probe: Chd8 cDNA2
Probe preparation: Antisense RNA labelled with digoxigenin
Visualized with: Alkaline phosphatase
Results
Specimen 2d E16: embryonic day 16.0 (more )
Note: coronal section
Structure Level Pattern Image Note
TS24: cerebral cortex subventricular zone Present 2d E16 Expression is present in the proliferative zones.
TS24: cerebral cortex ventricular layer Present 2d E16 Expression is present in the proliferative zones.
TS24: cortical subplate Present 2d E16

Specimen 2d P0: postnatal day 0 (more )
Note: coronal section
Structure Level Pattern Image Note
TS27: cerebral cortex subventricular zone Present 2d P0 Expression is present in the proliferative zones.
TS27: cerebral cortex ventricular zone Present 2d P0 Expression is present in the proliferative zones.
TS27: cortical subplate Present 2d P0

Specimen 2d P3 - coronal: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: cortical plate Present 2d P3 - left
TS27: hippocampus Present 2d P3 - left

Specimen 2d P3 - sagittal: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: cerebellum Present 2d P3 - right
TS27: corpus striatum Present 2d P3 - right
TS27: cortical plate Present 2d P3 - right
TS27: main olfactory bulb Present 2d P3 - right

Specimen 2d P7 - coronal: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: neocortex layer Present 2d P7 - left Expression is seen in the cortical plate.

Specimen 2d P7 - sagittal: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present 2d P7 - right
TS28: corpus striatum Present 2d P7 - right
TS28: hippocampus Present 2d P7 - right
TS28: main olfactory bulb Present 2d P7 - right
TS28: neocortex layer Present 2d P7 - right Expression is seen in the cortical plate.

Specimen 2d P14 - coronal: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Ambiguous 2d P14 - left Staining, or lack thereof, in this specimen was not described.

Specimen 2d P14 - sagittal: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: brain Ambiguous 2d P14 - right Staining, or lack thereof, in this specimen was not described.

Specimen 2d Adult - coronal: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Ambiguous 2d Adult - left Staining, or lack thereof, in this specimen was not described.

Specimen 2d Adult - sagittal: postnatal adult (more )
Structure Level Pattern Image Note
TS28: brain Ambiguous 2d Adult - right Staining, or lack thereof, in this specimen was not described.

Specimen 2e E16: embryonic day 16.0 (more )
Note: coronal section
Structure Level Pattern Image Note
TS24: cerebral cortex subventricular zone Strong 2e E16 Expression is present in the proliferative zones.
TS24: cerebral cortex ventricular layer Strong 2e E16 Expression is present in the proliferative zones.
TS24: cortical subplate Strong 2e E16

Specimen 2e P0: postnatal day 0 (more )
Note: coronal section
Structure Level Pattern Image Note
TS27: cerebral cortex subventricular zone Present 2e P0 Expression is present in the proliferative zones.
TS27: cerebral cortex ventricular zone Present 2e P0 Expression is present in the proliferative zones.
TS27: cortical subplate Present 2e P0

Specimen 2e P3: postnatal day 3 (more )
Note: coronal section
Structure Level Pattern Image Note
TS27: cortical plate Present 2e P3

Specimen 2e P7: postnatal day 7 (more )
Note: coronal section
Structure Level Pattern Image Note
TS28: neocortex layer Present 2e P7 Expression is seen in the cortical plate.

Specimen 2e Adult: postnatal adult (more )
Note: coronal section
Structure Level Pattern Image Note
TS28: cerebral cortex Ambiguous 2e Adult Staining, or lack thereof, in this specimen was not described.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory