About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:46142 Fuchs M, et al., Differential expression of MAM-subfamily protein tyrosine phosphatases during mouse development. Mech Dev. 1998 Jan;70(1-2):91-109
Assay type: RNA in situ
MGI Accession ID: MGI:5903114
Gene symbol: Ptprm
Gene name: protein tyrosine phosphatase, receptor type, M
Probe: PTPmu probe1
Probe preparation: Antisense RNA labelled with S35
Visualized with: Autoradiography
Results
Specimen day 8.5 not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Weak Diffuse

Specimen day 9.5 not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Weak Diffuse

Specimen 4A/B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: embryo Present Widespread 4A/B Speckled distribution of expression over entire embryo.
TS20: blood vessel Strong 4A/B
TS20: brain Strong Regionally restricted 4A/B
TS20: hypothalamus Very strong 4A/B
TS20: thalamus Very strong 4A/B
TS20: heart Present 4A/B

Specimen 4D/E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: embryo Present Widespread 4D/E Speckled distribution of expression over entire embryo.
TS22: blood vessel Strong 4D/E
TS22: brain meninges Present 4D/E
TS22: choroid plexus Present 4D/E
TS22: corpus striatum Present 4D/E
TS22: neocortex Present 4D/E
TS22: inferior colliculus Strong 4D/E
TS22: medulla oblongata Strong 4D/E
TS22: pons Strong 4D/E

Specimen 4G/H: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: brain meninges Present 4G/H
TS26: main olfactory bulb Present 4G/H
TS26: cerebellum Purkinje cell layer Present 4G/H
TS26: dental papilla Strong 4G/H
TS26: heart Strong 4G/H
TS26: metanephros Strong 4G/H
TS26: brown fat Strong Regionally restricted 4G/H Intense expression in brown fat in neck.
TS26: lung vascular element Strong Regionally restricted 4G/H Prominent expression in lungs, confined to endothelial cells of caillaries and larger blood vessels.
TS26: alimentary system vascular element Strong Regionally restricted 4G/H High levels of expression in blood vessels of submucosa of stomach and intestine.

Specimen 5A1/A2: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain blood vessel Present 5A1/A2
TS22: lateral ventricle choroid plexus Present 5A1/A2
TS22: meninges Present 5A1/A2
TS22: telencephalon Present Regionally restricted 5A1/A2 Expression in cerebral neuroepithelium.
TS22: corpus striatum Present 5A1/A2
TS22: thalamus Present Regionally restricted 5A1/A2 Expression in posterior thalamus.
TS22: nose Present Regionally restricted 5A1/A2 Expression in olfactory anlage.

Specimen 5C1/C2: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung vascular element Present Regionally restricted 5C1/C2 Expression strictly confined to pulmonary capillaries and blood vessels.
TS22: lobar bronchus epithelium Absent 5C1/C2 No expression in epithelial lining of bronchial tree.

Specimen 5D1/D2: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: liver vasculature Present 5D1/D2
TS22: dorsal aorta Present Regionally restricted 5D1/D2 Expression in endothelial lining of aorta, vena cava, mesenteric and umbilical blood vessls.
TS22: mesenteric artery Present Regionally restricted 5D1/D2 Expression in endothelial lining of aorta, vena cava, mesenteric and umbilical blood vessls.
TS22: mesenteric vein Present Regionally restricted 5D1/D2 Expression in endothelial lining of aorta, vena cava, mesenteric and umbilical blood vessls.
TS22: umbilical artery Present Regionally restricted 5D1/D2 Expression in endothelial lining of aorta, vena cava, mesenteric and umbilical blood vessls.
TS22: umbilical vein Present Regionally restricted 5D1/D2 Expression in endothelial lining of aorta, vena cava, mesenteric and umbilical blood vessls.
TS22: vena cava Present Regionally restricted 5D1/D2 Expression in endothelial lining of aorta, vena cava, mesenteric and umbilical blood vessls.
TS22: alimentary system vascular element Present Regionally restricted 5D1/D2 Expression in blood vessels of submucosa and muscularis underlying intestinal epithelia.

Specimen 6B1/B2: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: midgut vascular element Present Regionally restricted 6B1/B2 Expression in subucosa and muscularis of midgut, confined to small blood vessels and larger arteries. No expression in epithelial layer.
TS22: midgut epithelium Absent 6B1/B2

Specimen 6D1/D2: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: renal vasculature Present Regionally restricted 6D1/D2 Expression strictly restricted to renal and adrenal vasculature.

Specimen 6E1/E2: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: submandibular gland Present Regionally restricted 6E1/E2 Expression in endothelal cells of capillaries and small blood vessels between the parenchyma.

Specimen 7B1/B2: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: retina layer Present Regionally restricted 7B1/B2 Expression predominantly in ganglionic layer of neural retina.

Specimen 7D1/D2: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pancreas Present Regionally restricted 7D1/D2 Expression in endothelal cells of capillaries and small blood vessels between the parenchyma.

Specimen 7F1/F2: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: stomach vascular element Present Regionally restricted 7F1/F2 Speckled distribution of expression confined to blood vessels in submucosa and muscularis layers of stomach.

Specimen 10B/E: postnatal day 4.5 (more )
Structure Level Pattern Image Note
TS28: corpus striatum Present 10B/E
TS28: pallidum Absent 10B/E
TS28: cingulate cortex Weak Regionally restricted 10B/E Lower levels of expression in infragranular part of cingulate and central neocortex.
TS28: neocortex Weak Regionally restricted 10B/E Lower levels of expression in infragranular part of cingulate and central neocortex.
TS28: hypothalamus Weak Diffuse 10B/E
TS28: thalamus Weak Diffuse 10B/E

Specimen 11C/D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Strong 11C/D
TS28: main olfactory bulb Strong 11C/D
TS28: hippocampus Absent 11C/D
TS28: cerebellum Purkinje cell layer Strong 11C/D
TS28: cerebellum white matter Absent 11C/D

Specimen 12B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus Absent 12B

Specimen 12E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 12E
TS28: cerebellum white matter Absent 12E


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/12/2021
MGI 6.17
The Jackson Laboratory