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Gene Expression Data
Assay Details
Assay
Reference: J:217689 Guzman-Ayala M, et al., Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast. Development. 2015 Jan 1;142(1):118-27
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5812131
Gene symbol: Parp1
Gene name: poly (ADP-ribose) polymerase family, member 1
Antibody: anti-cleaved PARP (D214, 9544)
Assay notes: The antibody used recognizes the cleaved form of the protein.
Results
Specimen 3B Control: embryonic day 5.5 (more )
Structure Level Pattern Image Note
TS8: embryo Trace Single cells 3B Control There were no cleaved Parp1 cells in 16/20 embryos and 1 or 2 cleaved Parp cells in 4/20 embryos (shown).
Specimen 3B Cdh1-/-: embryonic day 5.5; Chd1tm1b(KOMP)Rsan/Chd1tm1b(KOMP)Rsan (more )
Structure Level Pattern Image Note
TS8: embryo Present Single cells 3B Cdh1-/- There were more than five cleaved Parp1 cells in 7/7 embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory