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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5540787
Gene symbol: Aadac
Gene name: arylacetamide deacetylase
Probe: RIKEN clone 2010015B04 subclone
Probe preparation: Antisense RNA labelled with digoxigenin
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:9034: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: urinary system Present Regionally restricted GUDMAP:9034
TS23: metanephros Present Regionally restricted GUDMAP:9034
TS23: renal cortex Present Regionally restricted GUDMAP:9034
TS23: cortical renal tubule Present Regionally restricted GUDMAP:9034
TS23: early proximal tubule Present Regionally restricted GUDMAP:9034 strong expression detected in a subset of early proximal tubules of maturing nephrons and likely absent from segment 1 at the urinary pole of maturing renal corpuscles
TS23: maturing nephron Present Regionally restricted GUDMAP:9034
TS23: late tubule Present GUDMAP:9034
TS23: renal medulla Present Regionally restricted GUDMAP:9034
TS23: immature loop of Henle Present Regionally restricted GUDMAP:9034 expression absent from deep within medulla but weakly detected in portion of loop of Henle closest to the cortex
TS23: developing capillary loop stage nephron group Present Regionally restricted GUDMAP:9034
TS23: anlage of loop of Henle of cortical renal tubule Present GUDMAP:9034 weak expression
TS23: renal capsule Absent GUDMAP:9034
TS23: nephrogenic zone Absent GUDMAP:9034
TS23: nephrogenic interstitium Absent GUDMAP:9034
TS23: cap mesenchyme Absent GUDMAP:9034
TS23: pretubular aggregate Absent GUDMAP:9034
TS23: ureteric tip Absent GUDMAP:9034
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:9034
TS23: renal vesicle Absent GUDMAP:9034
TS23: comma-shaped body Absent GUDMAP:9034
TS23: upper limb of comma-shaped body Absent GUDMAP:9034
TS23: lower limb of comma-shaped body Absent GUDMAP:9034
TS23: s-shaped body Absent GUDMAP:9034
TS23: renal connecting tubule of s-shaped body Absent GUDMAP:9034
TS23: distal segment of s-shaped body Absent GUDMAP:9034
TS23: medial segment of s-shaped body Absent GUDMAP:9034
TS23: proximal segment of s-shaped body Absent GUDMAP:9034
TS23: visceral epithelium of s-shaped body Absent GUDMAP:9034
TS23: parietal epithelium of s-shaped body Absent GUDMAP:9034
TS23: capillary loop renal corpuscle Absent GUDMAP:9034
TS23: visceral epithelium of capillary loop renal corpuscle Absent GUDMAP:9034
TS23: parietal epithelium of capillary loop renal corpuscle Absent GUDMAP:9034
TS23: presumptive mesangium of capillary loop renal corpuscle Absent GUDMAP:9034
TS23: presumptive endothelium of capillary loop renal corpuscle Absent GUDMAP:9034
TS23: associated interstitium of capillary loop renal corpuscle Absent GUDMAP:9034
TS23: maturing renal corpuscle Absent GUDMAP:9034
TS23: maturing glomerular tuft Absent GUDMAP:9034
TS23: glomerular capillary system of maturing glomerular tuft Absent GUDMAP:9034
TS23: glomerular basement membrane of maturing renal corpuscle Absent GUDMAP:9034
TS23: glomerular mesangium of maturing glomerular tuft Absent GUDMAP:9034
TS23: visceral epithelium of maturing renal corpuscle Absent GUDMAP:9034
TS23: Bowman's capsule of maturing renal corpuscle Absent GUDMAP:9034
TS23: parietal epithelium of maturing renal corpuscle Absent GUDMAP:9034
TS23: glomerular mesangium of maturing renal corpuscle Absent GUDMAP:9034
TS23: juxtaglomerular arteriole Absent GUDMAP:9034
TS23: renal medullary interstitium Absent GUDMAP:9034
TS23: renal medullary vasculature Absent GUDMAP:9034
TS23: renal medullary arterial system Absent GUDMAP:9034
TS23: renal medullary venous system Absent GUDMAP:9034
TS23: renal medullary capillary Absent GUDMAP:9034
TS23: medullary collecting duct Absent GUDMAP:9034
TS23: renal calyx Absent GUDMAP:9034
TS23: renal pelvis Absent GUDMAP:9034
TS23: pelvic urothelial lining Absent GUDMAP:9034
TS23: pelvic smooth muscle Absent GUDMAP:9034
TS23: perihilar interstitium Absent GUDMAP:9034
TS23: collecting duct Absent GUDMAP:9034
TS23: renal interstitium Absent GUDMAP:9034
TS23: renal vasculature Absent GUDMAP:9034
TS23: early nephron Absent GUDMAP:9034
TS23: cortical collecting duct Absent GUDMAP:9034
TS23: renal cortical interstitium Absent GUDMAP:9034
TS23: renal cortical vasculature Absent GUDMAP:9034
TS23: renal cortical arterial system Absent GUDMAP:9034
TS23: renal cortical venous system Absent GUDMAP:9034
TS23: renal cortical capillary Absent GUDMAP:9034
TS23: renal connecting tubule Absent GUDMAP:9034
TS23: early distal tubule Ambiguous GUDMAP:9034 possible expression in maturing nephrons and expression likely absent from early distal tubules of capillary loop nephrons
TS23: cortical renal tubule of maturing nephron group Present Regionally restricted GUDMAP:9034
TS23: early proximal tubule of maturing nephron Present Regionally restricted GUDMAP:9034
TS23: cortical renal tubule of capillary loop nephron group Present Regionally restricted GUDMAP:9034 weak expression
TS23: distal renal vesicle Absent GUDMAP:9034
TS23: proximal renal vesicle Absent GUDMAP:9034
TS23: renal connecting segment of renal vesicle Absent GUDMAP:9034
TS23: renal connecting segment of comma-shaped body Absent GUDMAP:9034
TS23: renal connecting tubule of capillary loop nephron Absent GUDMAP:9034
TS23: renal connecting tubule of maturing nephron Absent GUDMAP:9034
TS23: early distal tubule of maturing nephron Ambiguous GUDMAP:9034 possible expression
TS23: early distal tubule of capillary loop nephron Ambiguous GUDMAP:9034
TS23: early proximal tubule of capillary loop nephron Ambiguous GUDMAP:9034 expression absent from at least a portion of the early proximal tubule of capillary loop nephrons

Specimen GUDMAP:9035: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: ureter Absent GUDMAP:9035
TS23: urothelium of ureter Absent GUDMAP:9035
TS23: superficial cell layer of ureter Absent GUDMAP:9035
TS23: intermediate cell layer of ureter Absent GUDMAP:9035
TS23: basal cell layer of ureter Absent GUDMAP:9035
TS23: ureteral mesenchyme Absent GUDMAP:9035
TS23: ureteral mesenchyme subepithelial layer Absent GUDMAP:9035
TS23: ureteral smooth muscle layer Absent GUDMAP:9035
TS23: ureteral smooth muscle layer smooth muscle component Absent GUDMAP:9035
TS23: ureteral smooth muscle layer interstitium Absent GUDMAP:9035
TS23: ureteral mesenchyme outer layer Absent GUDMAP:9035
TS23: ureteral vasculature Absent GUDMAP:9035

Specimen GUDMAP:9477: embryonic day 10.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS17: genitourinary system mesenchyme Absent GUDMAP:9477
TS17: gonad primordium Absent GUDMAP:9477
TS17: mesonephros Absent GUDMAP:9477
TS17: mesonephros mesenchyme Absent GUDMAP:9477
TS17: mesonephric tubule Absent GUDMAP:9477
TS17: cranial mesonephric tubule Absent GUDMAP:9477
TS17: mesonephric glomerulus Absent GUDMAP:9477
TS17: rest of cranial mesonephric tubule Absent GUDMAP:9477
TS17: caudal mesonephric tubule Absent GUDMAP:9477
TS17: nephric duct, mesonephric portion Absent GUDMAP:9477
TS17: metanephric mesenchyme Absent GUDMAP:9477
TS17: nephric duct, metanephric portion Absent GUDMAP:9477

Specimen GUDMAP:9478: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: male reproductive system Present Regionally restricted GUDMAP:9478
TS21: mesonephros of male Present Regionally restricted GUDMAP:9478
TS21: mesonephric tubule of male Present GUDMAP:9478
TS21: testis Present Regionally restricted GUDMAP:9478
TS21: primary sex cord Present GUDMAP:9478
TS21: mesonephric mesenchyme of male Absent GUDMAP:9478
TS21: nephric duct of male, mesonephric portion Absent GUDMAP:9478
TS21: paramesonephric duct of male, mesonephric portion Absent GUDMAP:9478
TS21: coelomic epithelium of male mesonephros Absent GUDMAP:9478
TS21: nephric duct of male, rest of Absent GUDMAP:9478
TS21: epithelium of nephric duct of male Absent GUDMAP:9478
TS21: mesenchyme of nephric duct of male Absent GUDMAP:9478
TS21: paramesonephric duct of male, rest of Absent GUDMAP:9478
TS21: epithelium of rest of paramesonephric duct of male Absent GUDMAP:9478
TS21: mesenchyme of rest of paramesonephric duct of male Absent GUDMAP:9478
TS21: coelomic epithelium of testis Ambiguous GUDMAP:9478
TS21: interstitium of the testis Ambiguous GUDMAP:9478
TS21: developing vasculature of testis Ambiguous GUDMAP:9478

Specimen GUDMAP:9479: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP. Male and female were examined; only the male is shown. Annotators reported the male expression pattern in the metanephros is identical to female.
Structure Level Pattern Image Note
TS21: urogenital mesentery Absent GUDMAP:9479
TS21: metanephros Absent GUDMAP:9479
TS21: ureter Absent GUDMAP:9479

Specimen GUDMAP:9480: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP. Male and female were examined; only the male is shown. Annotators reported the male expression pattern in the bladder is identical to female.
Structure Level Pattern Image Note
TS21: ureter Absent GUDMAP:9480
TS21: primitive bladder Absent GUDMAP:9480
TS21: urothelium of primitive bladder Absent GUDMAP:9480
TS21: mesenchymal layer of primitive bladder Absent GUDMAP:9480

Specimen GUDMAP:9481: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: female reproductive system Present Regionally restricted GUDMAP:9481
TS21: mesonephros of female Present Regionally restricted GUDMAP:9481
TS21: mesonephric tubule of female Present GUDMAP:9481
TS21: mesonephric mesenchyme of female Absent GUDMAP:9481
TS21: nephric duct of female, mesonephric portion Absent GUDMAP:9481
TS21: paramesonephric duct of female, mesonephric portion Absent GUDMAP:9481
TS21: coelomic epithelium of female mesonephros Absent GUDMAP:9481
TS21: nephric duct of female, rest of Absent GUDMAP:9481
TS21: epithelium of nephric duct of female Absent GUDMAP:9481
TS21: mesenchyme of nephric duct of female Absent GUDMAP:9481
TS21: paramesonephric duct of female, rest of Absent GUDMAP:9481
TS21: epithelium of rest of paramesonephric duct of female Absent GUDMAP:9481
TS21: mesenchyme of rest of paramesonephric duct of female Absent GUDMAP:9481
TS21: ovary Ambiguous GUDMAP:9481 possible weak expression

Specimen GUDMAP:10927: postnatal adult (more )
Note: This animal was sexually mature. Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: metanephros Absent GUDMAP:10927

Specimen GUDMAP:10928: postnatal adult (more )
Note: This animal was sexually mature. Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: ureter Absent GUDMAP:10928


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/09/2022
MGI 6.21
The Jackson Laboratory