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Gene Expression Data
Assay Details
Assay
Reference: J:133947 Summerhurst K, et al., 3D representation of Wnt and Frizzled gene expression patterns in the mouse embryo at embryonic day 11.5 (Ts19). Gene Expr Patterns. 2008 May;8(5):331-48
Assay type: RNA in situ
MGI Accession ID: MGI:5447983
Gene symbol: Wnt4
Gene name: wingless-type MMTV integration site family, member 4
Probe: Wnt4 cDNA8
Probe preparation: Antisense RNA
Assay notes: These data are obtained from optical projection tomography (OPT).
Results
Specimen 1C: embryonic day 11.5 (more )
Note: Left side is OPT reconstructed data, right side is the corresponding whole-mount in situ hybridized embryo.
Structure Level Pattern Image Note
TS19: telencephalon Strong 1C
TS19: midbrain ventricular layer Present 1C
TS19: telencephalon ventricular layer Present 1C
TS19: midbrain Weak 1C
Specimen Table 1: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: 1st branchial arch Present
TS19: 2nd branchial arch Present
TS19: alimentary system Present
TS19: diencephalon Present
TS19: forelimb bud ectoderm Present
TS19: forelimb bud mesenchyme Present
TS19: fronto-nasal process Present
TS19: hindbrain Present
TS19: midbrain Present
TS19: neural tube Present
TS19: reproductive system Present
TS19: surface ectoderm Present
TS19: telencephalon Present
TS19: urinary system Present
TS19: inner ear Present Regionally restricted otic vesicle
Specimen 4C: embryonic day 11.5 (more )
Note: virtual section
Structure Level Pattern Image Note
TS19: hindbrain floor plate Present Regionally restricted 4C Expression is restricted to a very localized region of the ventral marginal floor plate.
Specimen 4D: embryonic day 11.5 (more )
Note: virtual section
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 4D From just posterior to the otic vesicle expression was detected along the length of the neural tube, in different dorsoventral domains depending on the anterior/posterior level.
TS19: neural tube Present Regionally restricted 4D From just posterior to the otic vesicle expression was detected along the length of the neural tube, in different dorsoventral domains depending on the anterior/posterior level.
Specimen 5 first: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 5_Wnt4 first
Specimen 5 second: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present 5_Wnt4 second Expression is in localized patches of proximal limb mesenchyme.
Specimen 5 third: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present 5_Wnt4 third Expression is in localized patches of proximal limb mesenchyme.
Specimen 5 fourth: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present 5_Wnt4 fourth Expression is in localized patches of proximal limb mesenchyme.
Specimen 5 fifth: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present 5_Wnt4 fifth Expression is in localized patches of proximal limb mesenchyme.
Specimen 5 sixth: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present 5_Wnt4 sixth Expression is in localized patches of proximal limb mesenchyme.
Specimen 5 seventh: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present 5_Wnt4 seventh Expression is in localized patches of proximal limb mesenchyme.
Specimen Table 2: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Regionally restricted Expression is in localized patches of proximal limb mesenchyme associated with pre-muscle masses.
Specimen Table S1: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Present Highest in posterior telencephalon.
TS19: telencephalon ventricular layer Strong
TS19: 1st branchial groove Present
TS19: branchial arch ectoderm Present
TS19: diencephalon Present
TS19: frontal process ectoderm Present
TS19: mandibular process Present
TS19: maxillary process Present
TS19: metanephric mesenchyme Present
TS19: midbrain ventricular layer Present
TS19: brain Present Regionally restricted Choroid plexus.
TS19: cortical hem Present
TS19: hindbrain floor plate Present Regionally restricted Expression is restricted to a very localized region of the ventral marginal floor plate, absent in preotic hindbrain.
TS19: hindbrain Present Regionally restricted Posterior to otic vesicle and throughout neural tube there is a broad ventricular domain from dorsal to ventral of midline, in most anterior part (until just below level of forelimb) - two elevated regions within domain, dorsal and ventral of midline.
TS19: neural tube Present Regionally restricted Posterior to otic vesicle and throughout neural tube there is a broad ventricular domain from dorsal to ventral of midline, in most anterior part (until just below level of forelimb) - two elevated regions within domain, dorsal and ventral of midline.
TS19: forelimb bud mesenchyme Present Patchy
TS19: forelimb bud ectoderm Present Regionally restricted Proximoventral limb ectoderm.
TS19: inner ear Present Regionally restricted Expression is in otic vesicle; highest in posterior lateral wall (future semicircular canal).
TS19: midgut Present Regionally restricted Expression is in the lining.
TS19: urinary system Present Regionally restricted Expression is in the urogenital ridge.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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