Mdm2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:49215 Leveillard T, et al., MDM2 expression during mouse embryogenesis and the requirement of p53. Mech Dev. 1998 Jun;74(1-2):189-93
Assay type:	RNA in situ
MGI Accession ID:	MGI:5442810
Gene symbol:	Mdm2
Gene name:	transformed mouse 3T3 cell double minute 2

Probe:	mdm2 probe2
Probe preparation:	Antisense RNA

Results

Specimen E10.5: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: dermomyotome	Present
TS17: embryo	Present

Specimen E11.5: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: dermomyotome	Present
TS19: embryo	Present

Specimen E12.5: embryonic day 12.5 (more

)

Specimen E14.5: embryonic day 14.5 (more

)

Structure	Level	Note
TS22: bronchus	Strong
TS22: esophagus	Strong
TS22: nasal cavity epithelium	Strong
TS22: testis	Strong
TS22: cerebral cortex	Present
TS22: lung mesenchyme	Present
TS22: tooth	Present
TS22: renal cortex	Ambiguous
TS22: thymus primordium	Ambiguous
TS22: intestine	Absent
TS22: liver	Absent
TS22: salivary gland	Absent
TS22: skeletal muscle	Absent
TS22: hindgut epithelium	Absent	No expression in colon epithelium.

Specimen E18.5: embryonic day 18.5 (more

)

Structure	Level	Pattern	Note
TS26: nasopharynx	Strong
TS26: pharyngo-tympanic tube	Strong
TS26: testis	Strong
TS26: lens	Present
TS26: tooth	Present
TS26: trachea	Present
TS26: retina	Present	Regionally restricted	Expression in inner and outer layers.

1c ©

Specimen 1c: embryonic day 14.5 (more

)

Structure	Level	Image
TS22: nasal cavity epithelium	Strong	1c
TS22: testis	Strong	1c
TS22: upper jaw incisor	Strong	1c
TS22: bronchus	Present	1c
TS22: cerebral cortex	Present	1c

2c ©

Specimen 2c: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: nasal cavity epithelium	Strong		2c
TS22: olfactory epithelium	Absent		2c

2h/i ©

Specimen 2h/i: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: incisor	Present
TS26: molar	Present
TS26: lower jaw incisor	Present	Regionally restricted	2h/i	Expression in ameloblasts and more weakly in odontoblasts.

3a/b ©

Specimen 3a/b: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: nasal cavity epithelium	Present		3a/b

3c/d ©

Specimen 3c/d: embryonic day 14.5; Trp53^tm1Tyj/Trp53^tm1Tyj (more

)

Structure	Level	Pattern	Image	Note
TS22: nasal cavity epithelium	Present		3c/d

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23