Gene Expression Data
Assay Details
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Assay
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Reference:
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J:159888
Sephton CF, et al., TDP-43 is a developmentally regulated protein essential for early embryonic development. J Biol Chem. 2010 Feb 26;285(9):6826-34
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5438542
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Gene symbol:
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Tardbp
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Gene name:
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TAR DNA binding protein
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
5A.i.:
embryonic day 9.5; TardbpGt(RRB030)Byg/Tardbp +
(more  )
Note: Embryos were fixed in 1% paraformaldehyde, 0.2% glutaraldehyde.
Specimen
5A.i.:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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Note:
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Embryos were fixed in 1% paraformaldehyde, 0.2% glutaraldehyde.
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Specimen
5A.ii.:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
5B.1:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: future brain |
Strong |
Regionally restricted |
5B.1
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Expression is present in the neuroepithelium.
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Specimen
5B.2:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: future brain |
Strong |
Regionally restricted |
5B.2
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Expression is present in the neuroepithelium.
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Specimen
5B.3:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
5B.4:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
5B.5:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
5B.6:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
5B.7:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
5B.8:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
6B.i:
embryonic day 10.5; TardbpGt(RRB030)Byg/Tardbp +
(more )
Note: Embryos were fixed in 1% paraformaldehyde, 0.2% glutaraldehyde.
Specimen
6B.i:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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Note:
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Embryos were fixed in 1% paraformaldehyde, 0.2% glutaraldehyde.
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Specimen
6B.ii:
embryonic day 10.5; TardbpGt(RRB030)Byg/Tardbp +
(more )
Note: Embryos were fixed in 1% paraformaldehyde, 0.2% glutaraldehyde.
Specimen
6B.ii:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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Note:
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Embryos were fixed in 1% paraformaldehyde, 0.2% glutaraldehyde.
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Specimen
6B.iii:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
6C.i:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
6C.ii:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
7i.:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
7ii.:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
7iii.:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
7iv.:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
7v.:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: spinal cord |
Present |
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7v
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Staining is obsered throughout the spinal cord, mostly in the dorsal horn and, to a lesser extent, the ventral horn.
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| TS28: spinal cord dorsal horn |
Present |
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7v
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Staining is obsered throughout the spinal cord, mostly in the dorsal horn and, to a lesser extent, the ventral horn.
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| TS28: spinal cord ventral horn |
Present |
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7v
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Staining is obsered throughout the spinal cord, mostly in the dorsal horn and, to a lesser extent, the ventral horn.
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Specimen
7vi.:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
7vii.:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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postnatal adult
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Sex:
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Female
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
7viii.:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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postnatal adult
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Sex:
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Male
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
7ix.:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: renal cortex |
Present |
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7ix
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Expression in the kidney is concentrated in the cortical region.
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Specimen
7x.:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: liver |
Moderate |
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7x
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Expression is present in the hepatocytes.
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Specimen
7xi.:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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TardbpGt(RRB030)Byg/Tardbp+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: heart |
Moderate |
Widespread |
7xi
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