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Gene Expression Data
Assay Details
Assay
Reference: J:106092 Tissir F, et al., Expression of planar cell polarity genes during development of the mouse CNS. Eur J Neurosci. 2006 Feb;23(3):597-607
Assay type: RNA in situ
MGI Accession ID: MGI:4946669
Gene symbol: Prickle2
Gene name: prickle planar cell polarity protein 2
Probe: Prickle2 cDNA1
Probe preparation: Antisense RNA labelled with P33
Visualized with: Autoradiography
Results
Specimen 1I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: nervous system Moderate Diffuse 1I
TS17: limb Present 1I
TS17: embryo Present Non-Uniform 1I Expression was detected at moderate intensity in neural tissue, and to a lesser level in non-neural tissue, particularly in limb buds.

Specimen 2X: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nervous system Moderate Diffuse 2X Expression was moderately and diffusely expressed in neural tissue, more at caudal than rostral levels, and more in migration and postmitotic differentiation fields than in ventricular zones.

Specimen 2Y: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nervous system Moderate Diffuse 2Y Expression was moderately and diffusely expressed in neural tissue, more at caudal than rostral levels, and more in migration and postmitotic differentiation fields than in ventricular zones.

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: organ system Trace

Specimen Table 2: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brainstem Present Regionally restricted Expression was present in the cochleovestibular nuclei and very low or undetectable in the reticular formation.
TS25: cerebellum Present Regionally restricted Expression was present in the external granule layer.
TS25: diencephalon ventricular layer Ambiguous Expression was very low or undetectable.
TS25: midbrain tegmentum Ambiguous Expression was very low or undetectable.
TS25: midbrain ventricular layer Ambiguous Expression was very low or undetectable.
TS25: tectum Ambiguous Expression was very low or undetectable.
TS25: thalamus Present Regionally restricted Expression was detected in the dorsal and ventral thalamus.
TS25: hypothalamus Present
TS25: retina Ambiguous Regionally restricted Expression was very low or undetectable in the ventricular zone and ganglion cells.
TS25: cortical plate Present Regionally restricted Expression was detected in the cortical plate ventricular zone/subventricular zone and in the cortical plate proper.
TS25: corpus striatum Ambiguous Regionally restricted Expression was very low or undetectable in the striatum ventricular zone/subventricular zone and in the striatum.
TS25: main olfactory bulb Ambiguous Regionally restricted Expression was very low or undetectable in the olfactory bulb and the mitral cells.

Specimen 4G3: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brain Weak Widespread 4G3
TS25: brainstem Strong Regionally restricted 4G3 Expression was strong in the cochleovestibular nuclei.

Specimen 4G4: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: thalamus Strong Regionally restricted 4G4 Expression was strong in the dorsal thalamic nuclei.
TS25: cortical plate Strong Widespread 4G4 Expression was strong in all sectors of the cortical plate.

Specimen 5M: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cerebral cortex Present Graded 5M Expression in the cortical plate was high with a rostral to caudal decreasing gradient.
TS27: brain Weak Regionally restricted 5M Expression was weak in areas of the brain, including all periventricular zones and the rostral migratory stream.
TS27: rostral migratory stream Weak 5M
TS27: cerebellum external granule cell layer Weak 5M

Specimen Table 3: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Present
TS28: dentate gyrus Present
TS28: hippocampus pyramidal cell layer Present
TS28: main olfactory bulb granule cell layer Present
TS28: main olfactory bulb mitral cell layer Present
TS28: diencephalon Ambiguous Regionally restricted Expression was very low or undetectable in the diencephalon ventricular zone.
TS28: dorsal thalamus Ambiguous Expression was very low or undetectable.
TS28: hypothalamus Ambiguous Expression was very low or undetectable.
TS28: prethalamus Ambiguous Expression was very low or undetectable.
TS28: cerebral cortex Present Regionally restricted Expression was detected in the cortical plate proper but was very low or undetectable in the cortical plate ventricular zone/subventricular zone.
TS28: corpus striatum Ambiguous Regionally restricted Expression was very low or undetectable in the striatum and the ventricular zone/subventricular zone.
TS28: rostral migratory stream Ambiguous Regionally restricted Expression was very low or undetectable in the rostral migratory stream.

Specimen 6V: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: neocortex Weak Regionally restricted 6V Expression was weak in the outer half of the neocortical ribbon at the lateral aspect of the hemisphere.

Specimen 6W: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: neocortex Weak Regionally restricted 6W Expression was weak in the outer half of the neocortical ribbon at the lateral aspect of the hemisphere.

Specimen 6X: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: brain Weak 6X

Specimen 7H: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 7H Expression was prominent in the most superficial layers but undetectable in deep layers.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/12/2021
MGI 6.17
The Jackson Laboratory