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Gene Expression Data
Assay Details
Assay
Reference: J:106092 Tissir F, et al., Expression of planar cell polarity genes during development of the mouse CNS. Eur J Neurosci. 2006 Feb;23(3):597-607
Assay type: RNA in situ
MGI Accession ID: MGI:4946663
Gene symbol: Dvl1
Gene name: dishevelled segment polarity protein 1
Probe: Dvl1 cDNA1
Probe preparation: Antisense RNA labelled with P33
Visualized with: Autoradiography
Results
Specimen 1C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present 1C

Specimen 2G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: brain Present 2G
TS20: cranial ganglion Present 2G
TS20: dorsal root ganglion Present 2G
TS20: lens vesicle Present 2G
TS20: liver Present 2G
TS20: retina Present 2G

Specimen 2H & 2I: embryonic day 12.5 (more )
Note: Fig. 2I is a higher magnification image of the boxed region if Fig. 2H.
Structure Level Pattern Image Note
TS20: brain Present 2H , 2I Expression was localized equally to periventricular zones and postmitotic neurons.
TS20: brain ventricular layer Present 2H , 2I Expression was localized equally to periventricular zones and postmitotic neurons.

Specimen 3C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: embryo Moderate Diffuse 3C
TS22: nervous system Present 3C Expression levels were highest in neural tissue, retina.
TS22: retina Present 3C Expression levels were highest in neural tissue, retina.
TS22: telencephalon Strong 3C Expression in the telencephalon was particularly strong in the medial cortical field.
TS22: cerebral cortex Strong Regionally restricted 3C Expression in the telencephalon was particularly strong in the medial cortical field.

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: liver Present

Specimen Table 2: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brainstem Present Regionally restricted Expression was present in the reticular formation and the cochleovestibular nuclei.
TS25: cerebellum Present Regionally restricted Expression was present in the external granule layer.
TS25: diencephalon ventricular layer Present
TS25: hypothalamus Present
TS25: midbrain tegmentum Present
TS25: midbrain ventricular layer Present
TS25: tectum Present
TS25: thalamus Present Regionally restricted Expression was detected in the dorsal and ventral thalamus.
TS25: retina Strong Regionally restricted Expression was high in the ventricular zone and ganglion cells of the retina.
TS25: cortical plate Present Non-Uniform Expression was detected in the subventricular zone/ventricular zone and in the cortical plate proper.
TS25: corpus striatum Present Expression was detected in the ventricular zone/subventricular zone and in the striatum.
TS25: main olfactory bulb Present Expression was detected in the olfactory bulb and in the mitral cells.

Specimen 4C1: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brain Moderate Diffuse 4C1

Specimen 4C2: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brain Moderate Diffuse 4C2

Specimen 4C3: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brain Moderate Diffuse 4C3

Specimen 4C4: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brain Moderate Diffuse 4C4
TS25: central nervous system ganglion Moderate Diffuse 4C4
TS25: hair follicle Moderate Diffuse 4C4
TS25: head mesenchyme Moderate Diffuse 4C4
TS25: retina Moderate Diffuse 4C4
TS25: skin Moderate Diffuse 4C4

Specimen 5E: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: brain Moderate Widespread 5E Expression was moderate throughout the brain and all neuronal fields were labelled with comparable intensity, whereas periventricular fields were less positive.

Specimen 5F: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: brain Moderate Widespread 5F Expression was moderate throughout the brain and all neuronal fields were labelled with comparable intensity, whereas periventricular fields were less positive.

Specimen Table 3: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Strong
TS28: diencephalon Present Regionally restricted Expression was detected in the diencephalon ventricular zone.
TS28: dentate gyrus Present
TS28: dorsal thalamus Present
TS28: hippocampus pyramidal cell layer Present
TS28: hypothalamus Present
TS28: main olfactory bulb granule cell layer Present
TS28: main olfactory bulb mitral cell layer Present
TS28: prethalamus Present
TS28: cerebral cortex Present Regionally restricted Expression was detected in the cortical plate ventricular zone/subventricular zone and the cortical plate proper.
TS28: corpus striatum Present Regionally restricted Expression was present in the striatum and the ventricular zone/subventricular zone.
TS28: rostral migratory stream Present

Specimen 6G: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Present 6G
TS28: cerebral cortex Present 6G

Specimen 6H: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: corpus striatum Present Regionally restricted 6H Expression was intense and evenly distributed, both in ventricular zones and areas of neuronal maturation.
TS28: diencephalon Present Regionally restricted 6H Expression was intense and evenly distributed, both in ventricular zones and areas of neuronal maturation.
TS28: hindbrain Present Regionally restricted 6H Expression was intense and evenly distributed, both in ventricular zones and areas of neuronal maturation.
TS28: cerebral cortex Present 6H
TS28: hippocampus Present 6H

Specimen 6I: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Moderate Regionally restricted 6I Expression was moderate in all neuronal layers of the olfactory bulb.
TS28: rostral migratory stream Moderate 6I Expression was moderate in the rostral migratory stream.

Specimen 7C: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Present 7C
TS28: dentate gyrus Present 7C
TS28: hippocampus pyramidal cell layer Present 7C
TS28: main olfactory bulb Present 7C


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/19/2021
MGI 6.17
The Jackson Laboratory