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Gene Expression Data
Assay Details
Assay
Reference: J:54346 Ponce E, et al., Murine acid alpha-glucosidase: cell-specific mRNA differential expression during development and maturation. Am J Pathol. 1999 Apr;154(4):1089-96
Assay type: RNA in situ
MGI Accession ID: MGI:3846774
Gene symbol: Gaa
Gene name: glucosidase, alpha, acid
Probe: Gaa cDNA3
Probe preparation: Antisense RNA labelled with S35
Visualized with: Autoradiography
Results
Specimen 2B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Strong Single cells 2B Expression is in pyramidal and granule neurons.
TS28: meninges Moderate Single cells 2B Expression is in the meningeal cells of the pia mater-arachnoid.
TS28: hippocampus molecular layer Weak Single cells 2B

Specimen 2C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus Strong Single cells 2C
TS28: choroid plexus Strong 2C Expression is in cells lining the choroid plexus.

Specimen 2D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: inferior colliculus Strong Regionally restricted 2D Expression is in neurons adjacent to the cerebral aqueduct located in the inferior colliculus nucleus and dorsal tegmental nuclei.
TS28: midbrain tegmentum Strong Regionally restricted 2D Expression is in neurons adjacent to the cerebral aqueduct located in the inferior colliculus nucleus and dorsal tegmental nuclei.
TS28: white matter Weak Regionally restricted 2D Expression is in glial cells of the white matter.
TS28: brain ependyma Weak Regionally restricted 2D Expression is in ependymal lining cells.

Specimen 2E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: brainstem Strong Single cells 2E Expression is in neurons.
TS28: cerebellum Purkinje cell layer Strong Single cells 2E Expression is in neurons.

Specimen 2F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: seminiferous tubule Moderate 2F

Specimen 2H: postnatal adult (more )
Structure Level Pattern Image Note
TS28: endometrium stroma Weak Diffuse 2H
TS28: endometrium glandular epithelium Weak 2H

Specimen 2J: postnatal adult (more )
Structure Level Pattern Image Note
TS28: ventricle cardiac muscle Moderate Diffuse 2J

Specimen 2L: postnatal adult (more )
Structure Level Pattern Image Note
TS28: skeletal muscle Weak Regionally restricted 2L Expression is in myocytes in paraspinal muscle.

Specimen 2M: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: hypothalamus Moderate Regionally restricted 2M Expression is in differentiating neurons.

Specimen 2N: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: inner ear epithelium Moderate Regionally restricted 2N Expression is in the epithelial lining cells.

Specimen 2O: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: sympathetic ganglion Moderate 2O

Specimen 2P: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: seminiferous cord Moderate Regionally restricted 2P Expression is in epithelial cells.

Specimen Table 1 Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: telencephalon Present Non-Uniform Expression is moderate to high in neurons throughout, moderate in pia mater-arachnoid meningeal cells and in choroid plexus lining epithelial cells, and is very low in ependymal cells, very low to low in glial cells/white matter.
TS28: midbrain Present Non-Uniform Expression is moderate to high in neurons/colliculus and tegmental nuclei, very low to low in glial cells/white matter.
TS28: cerebellum Purkinje cell layer Strong
TS28: cerebellum Present Non-Uniform Expression is low to moderate in other neurons aside from the Purkinje cells, and is very low to low in glial cells/white matter.
TS28: brainstem Present Non-Uniform Expression is moderate to high in neurons, very low to low in glial cells/white matter.
TS28: spinal cord ventral horn Strong
TS28: sympathetic ganglion Strong
TS28: spinal cord Weak Non-Uniform Expression is very low to low in glial cells/white matter.
TS28: eye Trace Non-Uniform Expression is in cells of ganglion, internuclear, and outer layers, and in extraocular myocytes.
TS28: cardiac muscle tissue Weak
TS28: cerebellum granule cell layer Weak
TS28: cerebellum molecular layer Weak
TS28: cerebellum white matter Weak
TS28: endometrium stroma Weak
TS28: heart atrium Weak
TS28: heart ventricle Weak
TS28: lamina propria of vagina Weak
TS28: Sertoli cell Moderate
TS28: endometrium glandular epithelium Trace
TS28: endometrium luminal epithelium Trace
TS28: interstitium of the testis Trace
TS28: myometrium Trace
TS28: spermatogonium Trace
TS28: stomach Trace
TS28: epithelium of epididymis Moderate
TS28: epithelium of vagina Trace Regionally restricted Expression is in glandular epithelial cells.
TS28: cortical renal tubule Weak Regionally restricted Expression is in cortical tubulaar epithelial cells.
TS28: renal medulla Trace Regionally restricted Expression is in medullar tubular epithelial cells.
TS28: ganglion Weak Regionally restricted Expression is in neurons and intestinal ganglia.
TS28: intestine epithelium Trace Regionally restricted Expression is in stromal cells and in mucosal epithelial cells.
TS28: intestine mucosa Trace Regionally restricted Expression is in stromal cells and in mucosal epithelial cells.
TS28: colon Trace Regionally restricted Expression is in the colon lamina propria.
TS28: liver Weak Regionally restricted Expression is weak in hepatocytes and is absent in cells of ducts and portal area.
TS28: adrenal gland Trace Diffuse
TS28: lung Trace Diffuse
TS28: pancreas Trace Diffuse
TS28: spleen Trace Diffuse
TS28: thymus Trace Diffuse
TS28: skeletal muscle Weak Expression is in myocytes. Included sections of the quadriceps, anterior tibialis, triceps, biceps, diaphragm, tongue, paraspinal, and extraocular muscle.
TS28: heart valve Absent

Specimen Table 2 E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Trace Ubiquitous

Specimen Table 2 E12: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: embryo Trace Ubiquitous

Specimen Table 2 E14: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: central nervous system Weak Ubiquitous
TS22: embryo Weak Non-Uniform Expression is very low to low in tissues outside the central nervous system.

Specimen Table 2 E16: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: central nervous system Moderate Regionally restricted Expression is weak to moderate in differentiating neurons.
TS24: inner ear Strong Regionally restricted Expression is in the epithelial lining cells.
TS24: peripheral nervous system Strong Regionally restricted Expression is in neurons.
TS24: sympathetic ganglion Strong
TS24: hypothalamus Moderate
TS24: seminiferous cord Moderate
TS24: intestine Weak
TS24: skeletal muscle Present Regionally restricted Expression is very low to low in myocytes in most muscle groups, moderate in myocytes of head and neck muscles.
TS24: atrium cardiac muscle Trace
TS24: ventricle cardiac muscle Trace
TS24: embryo Trace Regionally restricted Expression was very low to low in most cell types.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory