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Gene Expression Data
Assay Details
Assay
Reference: J:47185 Kamata T, et al., Isolation and characterization of a bovine neural specific protein (CRMP-2) cDNA homologous to unc-33, a C. elegans gene implicated in axonal outgrowth and guidance. Brain Res Mol Brain Res. 1998 Mar 1;54(2):219-36
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3813919
Gene symbol: Dpysl2
Gene name: dihydropyrimidinase-like 2
Antibody: Anti-CRMP-2 #N17
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Fixative: 5% acetic acid, 95% ethanol.
Results
Specimen 6A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: central nervous system Strong Ubiquitous 6A
TS24: peripheral nervous system Strong Ubiquitous 6A

Specimen 6B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: retina Present Regionally restricted 6B Expression was detected in the inner layer of the differentiating cells and growing axons of the ganglion cells, but not in the outer layer of the dividing cells.

Specimen 6C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: retina Present Regionally restricted 6C Expression was detected in the inner layer of the differentiating cells and growing axons of the ganglion cells, but not in the outer layer of the dividing cells.

Specimen 6D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: inner ear Present Regionally restricted 6D Expression was detected in the sensory hair cells.
TS24: cochlear ganglion Present 6D

Specimen 6E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: olfactory epithelium Present 6E Expression was detected in the dendrites, cell bodies and axons of the primary olfactory neurons.

Specimen 6F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: trigeminal ganglion Strong 6F

Specimen 6G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: myenteric nerve plexus Present Regionally restricted 6G Expression was detected in the myenteric plexus in the small intestine.

Specimen 7A,7D: embryonic day 16.5 (more )
Note: Fig. 7D is a higher magnification image of 7A. Coronal section at the level of the optic chiasma.
Structure Level Pattern Image Note
TS24: brain Strong Ubiquitous 7A
TS24: brain ventricular layer Absent 7A , 7D No expression was detected in the differentiated ependymal cells and choroidal plexus cells.
TS24: choroid plexus Absent 7A , 7D No expression was detected in the differentiated ependymal cells and choroidal plexus cells.

Specimen 7B,7E: embryonic day 16.5 (more )
Note: Fig. 7E is a higher magnification image of 7B. Coronal section at the level of the anterior pituitary.
Structure Level Pattern Image Note
TS24: brain Strong Ubiquitous 7B
TS24: cerebral cortex Present Regionally restricted 7B , 7E Expression was detected in the neuroepithelial cell zone. Very low levels of expression were seen in radial processes extending to the ventricular surface. High levels were detected in the upper differentiating zones.
TS24: cortical plate Present 7E , 7B Expression was highest in the apical dendrites growing to the outer surface from the neuronal cell bodies.
TS24: cortical subplate Present 7B , 7E Expression was high in the cytoplasm of the cell bodies and possibly the terminals of the contacting axons.
TS24: cerebral cortex intermediate zone Present 7B , 7E Expression was predominantly detected in the axons.
TS24: cerebral cortex subventricular zone Present 7B , 7E Expression was predominantly detected in the axons.

Specimen 7C,7F: embryonic day 16.5 (more )
Note: Fig. 7F is a higher magnification image of 7C. Coronal section at the level of the mammilary body.
Structure Level Pattern Image Note
TS24: brain Strong Ubiquitous 7C
TS24: pons Present Regionally restricted 7F , 7C Expression was detected in the transverse fibers of the pons.

Specimen 8A: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: brain Present Ubiquitous 8A

Specimen 8B: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: corpus callosum Present 8B

Specimen 8C: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: cingulate cortex Present 8C

Specimen 8D: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: external capsule Present 8D

Specimen 8E: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: fimbria hippocampus Strong 8E
TS28: fornix Strong 8E

Specimen 8F: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present 8F The dendrites and cell bodies of the pyramidal cells in the CA1 field of the hippocampus were stained.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/19/2021
MGI 6.17
The Jackson Laboratory