About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:103780 Maurer ME, et al., Endocytosis of megalin by visceral endoderm cells requires the Dab2 adaptor protein. J Cell Sci. 2005 Nov 15;118(Pt 22):5345-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3617842
Gene symbol: Eea1
Gene name: early endosome antigen 1
Antibody: anti-EEA1
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2B +/: embryonic day 6.5; Dab2tm1.1Cpr/Dab2+ (more )
Note: Wild-type embryos were either +/+ or +/-. This section is also stained with Dab2 as shown in assay MGI:3617839.
Structure Level Pattern Image Note
TS9: extraembryonic visceral endoderm Present Regionally restricted 2B Expression is in early endosomes.

Specimen 2D -/-: embryonic day 6.5; Dab2tm1.1Cpr/Dab2tm1.1Cpr (more )
Note: This section is also stained with Dab2 as shown in assay MGI:3617839.
Structure Level Pattern Image Note
TS9: extraembryonic visceral endoderm Weak Regionally restricted 2D Expression in early endosomes is reduced in this mutant.

Specimen 2F +/-: embryonic day 6.5; Dab2tm1.1Cpr/Dab2+ (more )
Note: Wild-type embryos were either +/+ or +/-. This section is also stained with Lrp2 (megalin) as shown in assay MGI:3617845.
Structure Level Pattern Image Note
TS9: extraembryonic visceral endoderm Present 2F Expression is in early endosomes.

Specimen 2H -/-: embryonic day 6.5; Dab2tm1.1Cpr/Dab2tm1.1Cpr (more )
Note: This section is also stained with Lrp2 (megalin) as shown in assay MGI:3617845.
Structure Level Pattern Image Note
TS9: extraembryonic visceral endoderm Weak 2H Expression in early endosomes is reduced in this mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/05/2021
MGI 6.17
The Jackson Laboratory