About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:103780 Maurer ME, et al., Endocytosis of megalin by visceral endoderm cells requires the Dab2 adaptor protein. J Cell Sci. 2005 Nov 15;118(Pt 22):5345-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3617845
Gene symbol: Lrp2
Gene name: low density lipoprotein receptor-related protein 2
Antibody: anti-megalin
Detection system: Secondary antibody coupled to Alexa Fluor
Assay notes: This section is also stained with EEA1 as shown in assay MGI:3617842.
Results
Specimen 2F +/?: embryonic day 6.5; Dab2tm1.1Cpr/Dab2+ (more )
Note: Littermate control; embryos were either +/+ or +/-. Double labeled: green - Lrp2; red - Eea1 (assay MGI:3617842).
Structure Level Pattern Image Note
TS9: extraembryonic visceral endoderm Present 2F Expression is at the apical surface and in apical and basolateral vesicles.
Specimen 2H -/-: embryonic day 6.5; Dab2tm1.1Cpr/Dab2tm1.1Cpr (more )
Note: Double labeled: green - Lrp2; red - Eea1 (assay MGI:3617842).
Structure Level Pattern Image Note
TS9: extraembryonic visceral endoderm Present 2H Expression is at the apical surface.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory