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Gene Expression Data
Assay Details
Assay
Reference: J:74049 Segat D, et al., Expression of matrilin-1, -2 and -3 in developing mouse limbs and heart. Matrix Biol. 2000 Dec;19(7):649-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3576372
Gene symbol: Matn2
Gene name: matrilin 2
Antibody: anti-matrilin 2
Detection system: Secondary antibody coupled to Cy3
Assay notes: The tissue was frozen, sectioned, and then fixed with 1% paraformaldehyde in PBS for 10 minutes.
Results
Specimen 1 9.5 dpc: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: heart Absent 1_9.5 dpc Matn2

Specimen 1 10.5 dpc: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: heart Present 1_10.5 dpc Matn2

Specimen 3 12.5 dpc: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: forelimb pre-cartilage condensation Absent 3_12.5 dpc Matn2

Specimen 3 13.5 dpc: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: hand mesenchyme Present 3_13.5 dpc Matn2 Expression is present in mesenchymal tissues surrounding the cartilage.

Specimen 3 14.5 dpc: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: forelimb skeleton Present 3_14.5 dpc Matn2 Expression is present in the area of the developing inter-phalangeal joints.

Specimen 4: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: radius Present 4_Matn2 Expression is present in the hypertrophic cartilage, in the perichondrium, and at the articular surface.
TS23: ulna Present 4_Matn2 Expression is present in the hypertrophic cartilage, in the perichondrium, and at the articular surface.

Specimen 5 15.5 dpc: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: forelimb skeleton Present 5_15.5 dpc Matn2 Expression is present in the perichondrium, within the cartilage matrix at the periphery of the developing bone.
TS24: hand mesenchyme Present Regionally restricted 5_15.5 dpc Matn2 Expression is present in the connective tissues surrounding the cartilage.
TS24: hand dermis Present 5_15.5 dpc Matn2

Specimen 5 17.5 dpc left: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: forelimb skeleton Present 5_17.5 dpc Matn2 left Expression is present in the perichondrium.
TS26: hand mesenchyme Present Regionally restricted 5_17.5 dpc Matn2 left Expression is present in the connective tissues surrounding the cartilage.
TS26: hand dermis Present Non-Uniform 5_17.5 dpc Matn2 left Expression is increased in the dermis at areas of insertion of the nail of the developing claw.

Specimen 5 17.5 dpc right: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: forelimb skeleton Present 5_17.5 dpc Matn2 right Expression is present in the perichondrium.
TS26: hand mesenchyme Present Regionally restricted 5_17.5 dpc Matn2 right Expression is present in the connective tissues surrounding the cartilage.
TS26: hand dermis Present Non-Uniform 5_17.5 dpc Matn2 right Expression is increased in the dermis at areas of insertion of the nail of the developing claw.

Specimen 6: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: humerus Present Non-Uniform 6_Matn2 Expression especially accumulates in the cell layers of the developing articular surface.
TS24: ulna Present Non-Uniform 6_Matn2 Expression especially accumulates in the cell layers of the developing articular surface.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory