About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:58691 Hildebrand JD, et al., Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice. Cell. 1999 Nov 24;99(5):485-97
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3037557
Gene symbol: Shroom3
Gene name: shroom family member 3
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 8.5-8.75; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS13: neural ectoderm Strong Regionally restricted 2A Expression was detected in the cranial neuroepithelium in the rostral portion of the embryo.
TS13: gut Present 2A
TS13: neural tube Present 2A
TS13: trunk paraxial mesenchyme Present 2A
TS13: head mesenchyme Absent 2A

Specimen 2B left: embryonic day 10.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS18: forebrain Present 2B left
TS18: gut Present 2B left
TS18: heart Present 2B left
TS18: neural tube Present 2B left
TS18: trunk somite Present 2B left
TS18: trunk Present Regionally restricted 2B left Expression was detected in the ventral body wall.

Specimen 2B right: embryonic day 10.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS18: forebrain Present 2B right
TS18: gut Present 2B right
TS18: heart Present 2B right
TS18: neural tube Present 2B right
TS18: trunk somite Present 2B right
TS18: trunk Present Regionally restricted 2B right Expression was detected in the ventral body wall.

Specimen 2C: embryonic day 12.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS20: embryo Present 2C

Specimen 2D: embryonic day 14.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS22: forebrain Present 2D
TS22: skeletal muscle Present 2D
TS22: hand Present Regionally restricted 2D Expression was detected in the distal tips of the digits.

Specimen 2E: embryonic day 8.5-8.75; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS13: neural ectoderm Strong Regionally restricted 2E Expression was detected in the cranial neuroepithelium in the rostral portion of the embryo.
TS13: gut Present Regionally restricted 2E Expression was detected in the foregut.
TS13: neural tube Present 2E
TS13: optic pit Present 2E
TS13: trunk paraxial mesenchyme Present 2E
TS13: head mesenchyme Absent 2E

Specimen 2F: embryonic day 8.5-8.75; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS13: neural tube Present 2F
TS13: trunk paraxial mesenchyme Present 2F
TS13: gut Present Regionally restricted 2F Expression was detected in the foregut.

Specimen 2G: embryonic day 8.5-8.75; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS13: neural tube Present 2G
TS13: trunk paraxial mesenchyme Present 2G
TS13: gut Present Regionally restricted 2G Expression was detected in the hindgut.

Specimen 2H: embryonic day 10.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS17: forebrain Present 2H
TS17: gut Present 2H
TS17: heart Present 2H
TS17: neural tube Present 2H
TS17: neural tube floor plate Present 2H
TS17: neural tube roof plate Present 2H
TS17: trunk somite Present 2H
TS17: trunk Present Regionally restricted 2H Expression was detected in the ventral body wall.

Specimen 2I: embryonic day 10.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS17: gut Present 2I
TS17: heart Present 2I
TS17: neural tube Present 2I
TS17: neural tube floor plate Present 2I
TS17: trunk somite Present 2I
TS17: trunk Present Regionally restricted 2I Expression was detected in the ventral body wall.

Specimen 2J: embryonic day 10.5; Shroom3Gt(ROSA53)Sor/Shroom3+ (more )
Structure Level Pattern Image Note
TS17: heart Present 2J
TS17: midgut Present 2J
TS17: neural tube Present 2J
TS17: neural tube floor plate Present 2J
TS17: neural tube roof plate Present 2J
TS17: trunk somite Present 2J
TS17: trunk Present Regionally restricted 2J Expression was detected in the ventral body wall.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/18/2020
MGI 6.14
The Jackson Laboratory