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Gene Expression Data
Assay Details
Assay
Reference: J:71241 Brown CB, et al., PlexinA2 and semaphorin signaling during cardiac neural crest development. Development. 2001 Aug;128(16):3071-80
Assay type: RNA in situ
MGI Accession ID: MGI:2154265
Gene symbol: Plxna2
Gene name: plexin A2
Probe: PlexinA2 cDNA
Probe preparation: Antisense RNA labelled with S35
Visualized with: Autoradiography
Results
Specimen 1A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord roof plate Strong 1A
TS20: spinal cord Present Regionally restricted 1A Expression throughout the ventral neural tube excluding the ventral horns.
TS20: dorsal root ganglion Present 1A

Specimen 1B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trunk mesenchyme Present Regionally restricted 1B Expression adjacent to the pulmonary trunk and aortic arch arteries.
TS20: arch of aorta Present 1B

Specimen 1C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: migrating neural crest Present Regionally restricted 1C The authors state that a column of expressing cells is seen extending into the outflow tract endocardial cushions consistent with expression by migrating cardiac neural crest.
TS20: outflow tract Present Regionally restricted 1C The authors state that a column of expressing cells is seen extending into the outflow tract endocardial cushions consistent with expression by migrating cardiac neural crest.

Specimen 4A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future brain Present 4A Expression in the neural folds.
TS13: neural tube Present 4A Expression in the neural folds.

Specimen 4B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Present Regionally restricted 4B Expression in the dorsal neural tube at the level of the first three somites, the region from which cardiac neural crest emerges.

Specimen 4C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube roof plate Present 4C

Specimen 4D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial arch Present 4D Expression throughout the pharyngeal arches.
TS17: arterial system Present 4D Expression surrounding the aortic arch arteries.

Specimen 4E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: bulbus cordis rostral half Present 4E

Specimen 4F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme Present Regionally restricted 4F Expressing cells surrounding the aorta and pulmonary trunk.
TS19: outflow tract Present Regionally restricted 4F Expression extedending into the outflow tract mesenchyme.
TS19: left ventricle cardiac muscle Present 4F

Specimen 5A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord roof plate Present 5A
TS20: spinal cord Present Regionally restricted 5A Expression excludes the ventral horns.
TS20: dorsal root ganglion Present 5A
TS20: outflow tract Present Regionally restricted 5A Expression around the aorta.
TS20: arterial system Present Regionally restricted 5A Expression in the ductus arteriosus.
TS20: trunk mesenchyme Present Regionally restricted 5A Expression surrounding the ductus arteriosus and dorsal aorta.

Specimen 5B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: outflow tract Present Regionally restricted 5B Expression in a population of cells in the condensed mesenchyme of the outflow tract where neural crest cells reside.
TS20: spinal cord roof plate Present 5B
TS20: trunk mesenchyme Present Regionally restricted 5B Expression surrounding the dorsal aorta.

Specimen 5C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: gut Present Regionally restricted 5C Expression in the smooth muscle of the intestines.

Specimen 5E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung Present 5E Expression in the bronchial smooth muscle.

Specimen 7B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: left ventricle cardiac muscle Weak 7B
TS20: heart Present Regionally restricted 7B A localized collection of expressing cells in the condensed mesnehcyme.

Specimen 7E: embryonic day 12.5; Pax3Sp/Pax3Sp (more )
Structure Level Pattern Image Note
TS20: left ventricle cardiac muscle Strong 7E
TS20: endocardial cushion Weak 7E


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/19/2021
MGI 6.17
The Jackson Laboratory