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Endonuclease-mediated Allele Detail
Symbol: Rbpjem2H
Name: recombination signal binding protein for immunoglobulin kappa J region; endonuclease-mediated mutation 2, Harwell
MGI ID: MGI:6451740
Synonyms: RBPJ-T223R-EM2-B6N
Gene: Rbpj  Location: Chr5:53555779-53657445 bp, + strand  Genetic Position: Chr5, 29.37 cM, cytoband C1-C3
Strain of Origin:  C57BL/6NTac
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Nucleotide substitutions
Mutation detailsCRISPR-targeting introduced the amino acid substitution of threonine with arginine at position 223 (T223R). (J:90559)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rbpj Mutation:  172 strains or lines available
Original:  J:90559 The Mammalian Genetics Unit at Harwell, Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK. Unpublished. 2004-2103;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory