Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Zic2iso
Name:	zinc finger protein of the cerebellum 2; isomeric
MGI ID:	MGI:6355448
Gene:	Zic2  Location: Chr14:122712847-122717264 bp, + strand  Genetic Position: Chr14, 65.97 cM
Alliance:	Zic2iso page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) (Modified isoform(s)) Mutation:    Single point mutation   Mutation details: The ENU-induced mutation is a C to A alteration that results in a stop-gain mutation of tyrosine 401 (p.Y401*) in the encoded protein. This disrupts the fifth zinc finger domain of the protein. (J:268103)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	45 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	13 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zic2 Mutation:	41 strains or lines available

Original:	J:268103 Dykes IM, et al., A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity. Sci Rep. 2018 Jul 11;8(1):10439
All:	1 reference(s)