Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Nfkb2m3Btlr
Name:	nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100; mutation 3, Bruce Beutler
MGI ID:	MGI:6305796
Synonyms:	lolita
Gene:	Nfkb2  Location: Chr19:46292759-46300824 bp, + strand  Genetic Position: Chr19, 38.8 cM, cytoband C3-D2
Alliance:	Nfkb2m3Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) (Not Specified) Mutation:    Single point mutation   Mutation details: T to C transition at base pair 46,307,720 (v38) on chromosome 19, or base pair 3,743 in the GenBank genomic regionNC_000085.The effect of the mutation at the cDNA and protein levels has not been examined, but the mutation is predicted to result in skipping of the 159-base pair exon 8. The mutation would cause an in-frame deletion of 53 amino acids beginning after amino acid 168 of the protein, which is normally 899 amino acids in length. (J:274960) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfkb2 Mutation:	49 strains or lines available

Original:	J:274960 Choi JH, et al., Mutagenetix entry for lolita. MGI Direct Data Submission. 2019;
All:	1 reference(s)