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Cd36tm1.1Ijg
Targeted Allele Detail
Summary
Symbol: Cd36tm1.1Ijg
Name: CD36 molecule; targeted mutation 1.1, Ira J Goldberg
MGI ID: MGI:6194992
Gene: Cd36  Location: Chr5:17986688-18093799 bp, - strand  Genetic Position: Chr5, 8.11 cM
Alliance: Cd36tm1.1Ijg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:264105
Parent Cell Line:  KV1 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe targeting vector is designed to insert a loxP site upstream of exon 3, and an FRT-flanked neomycin selection cassette, followed by a second loxP site, downstream of exon 4. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 3 through 4 floxed. (J:264105)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd36 Mutation:  32 strains or lines available
References
Original:  J:264105 Son NH, et al., Endothelial cell CD36 optimizes tissue fatty acid uptake. J Clin Invest. 2018 Jul 26;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory