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Klhl20tm1.1Rhch
Targeted Allele Detail
Summary
Symbol: Klhl20tm1.1Rhch
Name: kelch-like 20; targeted mutation 1.1, Ruey-Hwa Chen
MGI ID: MGI:5781141
Synonyms: KLHL20fl/fl
Gene: Klhl20  Location: Chr1:160915945-160959078 bp, - strand  Genetic Position: Chr1, 69.75 cM
Alliance: Klhl20tm1.1Rhch page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:232813
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe gene was targeted with a vector containing a loxP site in intron 2 and an FRT-neo-FRT-loxP cassette in intron 6. Subsequent FLP-mediated recombination excised the neo cassette, leaving exons 3-6 floxed. (J:232813)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Klhl20 Mutation:  36 strains or lines available
References
Original:  J:232813 Liu CC, et al., Cul3-KLHL20 Ubiquitin Ligase Governs the Turnover of ULK1 and VPS34 Complexes to Control Autophagy Termination. Mol Cell. 2016 Jan 7;61(1):84-97
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory