Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Gata6tm1Hadj
Name:	GATA binding protein 6; targeted mutation 1, Anna-Katerina Hadjantonakis
MGI ID:	MGI:5700508
Synonyms:	Gata6H2B-Venus, Gata6tm1(HIST1H2BB/Venus)Hadj
Gene:	Gata6  Location: Chr18:11052510-11085636 bp, + strand  Genetic Position: Chr18, 5.63 cM
Alliance:	Gata6tm1Hadj page

Germline Transmission:	Earliest citation of germline transmission: J:226600
Parent Cell Line:	KH2 (ES Cell)
Strain of Origin:	(C57BL/6 x 129S4/SvJae)F1

Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter) Mutation:    Insertion   Mutation details: The targeting vector is designed to insert downstream of the first non-coding intron with (from 3' to 5') an FRT site, engrailed 2 intron and exon with splice acceptor site, H2B-Venus-polyadenylation sequence, rox-flanked beta actin promoter driven NEO cassette, and a loxP site, followed by exon 2 and a second loxP site. Two alternative translation initiation codons are present in exon 2. (J:226600, J:227467)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gata6 Mutation:	32 strains or lines available

Original:	J:226600 Freyer L, et al., A loss-of-function and H2B-Venus transcriptional reporter allele for Gata6 in mice. BMC Dev Biol. 2015;15:38
All:	3 reference(s)