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Nr3c1tm1.1Jaci
Targeted Allele Detail
Nomenclature
Symbol: Nr3c1tm1.1Jaci
Name: nuclear receptor subfamily 3, group C, member 1; targeted mutation 1.1, John Cidlowski
MGI ID: MGI:5526027
Synonyms: GRloxP
Gene: Nr3c1  Location: Chr18:39410545-39519421 bp, - strand  Genetic Position: Chr18, 21.09 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:201995
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsLoxP sites were inserted in introns 2 and 4, together with a neomycin cassette flanked by Frt sites. Flp recombinase mediated recombination removed the neomycin cassette. (J:201995)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr3c1 Mutation:  21 strains or lines available
References
Original:  J:201995 Oakley RH, et al., Essential role of stress hormone signaling in cardiomyocytes for the prevention of heart disease. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):17035-40
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory