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Targeted Allele Detail
Symbol: Ptf1a/Ptf1aostm4Kymm
Name: pancreas specific transcription factor, 1a; targeted mutation 4, Ken-ichi Yamamura
MGI ID: MGI:5507999
Synonyms: Gm13336-Ptf1alacZ
Gene: Ptf1a  Location: Chr2:19445663-19447501 bp, + strand  Genetic Position: Chr2, 13.37 cM, cytoband A2
Germline Transmission:  Earliest citation of germline transmission: J:195133
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsRecombination of Ptf1a/Ptf1aostm1Kymm exchanged the floxed neomycin resistance cassette with with a lacZ gene, FRT site, puromycin resistance cassette and lox2272 site. This allele was generated in ES cells containing Etn2Sd. (J:195133)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptf1a Mutation:  18 strains or lines available
Original:  J:195133 Semba K, et al., Ectopic expression of Ptf1a induces spinal defects, urogenital defects, and anorectal malformations in Danforth's short tail mice. PLoS Genet. 2013 Feb;9(2):e1003204
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory