Ptf1a/Ptf1aostm1Kymm
Targeted Allele Detail
|
|
| Symbol: |
Ptf1a/Ptf1aostm1Kymm |
| Name: |
pancreas specific transcription factor, 1a; targeted mutation 1, Ken-ichi Yamamura |
| MGI ID: |
MGI:5502928 |
| Synonyms: |
Gm13336-Ptf1aneo |
| Gene: |
Ptf1a Location: Chr2:19450474-19452312 bp, + strand Genetic Position: Chr2, 13.37 cM, cytoband A2
|
| Alliance: |
Ptf1a/Ptf1aostm1Kymm page
|
|
| Germline Transmission: |
Earliest citation of germline transmission:
J:195133
|
| Parent Cell Line: |
Not Specified (ES Cell)
|
| Strain of Origin: |
Not Specified
|
|
| Allele Type: |
|
Targeted (Null/knockout) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: A loxP site, FRT site, neomycin resistance cassette, lox2272 site, polyadenylation sequence and FRT site replaced exon 1 of Ptf1a and exons 1 and 2 of Ptf1aos. RT-PCR confirmed the abscence of transcript expression of both transcripts in E9.5 embryos. This allele was generated in ES cells containing Etn2Sd.
(J:195133)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
| Carrying any Ptf1a Mutation: |
29 strains or lines available
|
|
| Original: |
J:195133 Semba K, et al., Ectopic expression of Ptf1a induces spinal defects, urogenital defects, and anorectal malformations in Danforth's short tail mice. PLoS Genet. 2013 Feb;9(2):e1003204 |
| All: |
1 reference(s) |
|
Analysis Tools
