About   Help   FAQ
Gt(ROSA)26Sortm1(Bmi1)Aiwa
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(Bmi1)Aiwa
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Atsushi Iwama
MGI ID: MGI:5496634
Synonyms: R26StopFLBmi1
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(Bmi1)Aiwa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:198331
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe targeting construct inserted a floxed neomycin resistance/STOP cassette, FLAG-tagged Bmi1 cDNA, IRES, EGFP and bovine polyadenylation sequence. (J:198331)
Generation of the Gt(ROSA)26Sortm1(Bmi1)Aiwa allele
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  944 strains or lines available
References
Original:  J:198331 Nakamura S, et al., Bmi1 confers resistance to oxidative stress on hematopoietic stem cells. PLoS One. 2012;7(5):e36209
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory