Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hprt1tm1(H1-RNAi:Tmsb4x)Prri
Name:	hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Paul Riley
MGI ID:	MGI:5487445
Synonyms:	Tbeta4 shRNA
Gene:	Hprt1  Location: ChrX:52077014-52110536 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Alliance:	Hprt1tm1(H1-RNAi:Tmsb4x)Prri page

Germline Transmission:	Earliest citation of germline transmission: J:195902
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted Mutation:    Insertion   Hprt1tm1(H1-RNAi:Tmsb4x)Prri involves 1 genes/genome features (Tmsb4x) View all   Mutation details: The expression cassette containing the H1 RNA polymerase III promoter, floxed STOP and the short hairpin RNA targeting Tmsb4x was inserted into the locus. (J:195902)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt1 Mutation:	1273 strains or lines available

Original:	J:195902 Rossdeutsch A, et al., Essential role for thymosin beta4 in regulating vascular smooth muscle cell development and vessel wall stability. Circ Res. 2012 Aug 3;111(4):e89-102
All:	3 reference(s)