Gt(ROSA)26Sortm1(CAG-Mir21)Jake
Targeted Allele Detail
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| Symbol: |
Gt(ROSA)26Sortm1(CAG-Mir21)Jake |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, John A Kessler |
| MGI ID: |
MGI:5474351 |
| Synonyms: |
ROSA-miR21 |
| Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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| Alliance: |
Gt(ROSA)26Sortm1(CAG-Mir21)Jake page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:192021
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
C57BL/6
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| Allele Type: |
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Targeted (Conditional ready, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Gt(ROSA)26Sortm1(CAG-Mir21)Jake expresses
1 gene
Knock-in expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Mir21a (MGI:2676885) |
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Mutation details: A cassette, consisting of the CAG (CMV-chicken beta actin) promoter, a splice acceptor site, a floxed pgk-neo stop construct, and the mouse Mir21 sequence, was inserted via homologous recombination. The primary Mir21 transcript used contains 381 base pairs.
(J:192021)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gt(ROSA)26Sor Mutation: |
942 strains or lines available
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| Original: |
J:192021 Bhalala OG, et al., microRNA-21 regulates astrocytic response following spinal cord injury. J Neurosci. 2012 Dec 12;32(50):17935-47 |
| All: |
1 reference(s) |
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Analysis Tools
