Calcatm1.1(cre/ERT2)Ptch
Targeted Allele Detail
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Symbol: |
Calcatm1.1(cre/ERT2)Ptch |
Name: |
calcitonin/calcitonin-related polypeptide, alpha; targeted mutation 1.1, Pao-Tien Chuang |
MGI ID: |
MGI:5460801 |
Synonyms: |
CGRPCreER |
Gene: |
Calca Location: Chr7:114230713-114235592 bp, - strand Genetic Position: Chr7, 59.99 cM
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Alliance: |
Calcatm1.1(cre/ERT2)Ptch page
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Germline Transmission: |
Earliest citation of germline transmission:
J:190366
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Parent Cell Line: |
E14 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Calcatm1.1(cre/ERT2)Ptch expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: A cre/ERT2 fusion construct followed by an FRT flanked PGK neo selection cassette was inserted into exon 2 at the ATG translational start site. The selection cassette was subsequently removed by crossing properly targeted mice to mice expressing flp recombinase.
(J:190366)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Calca
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Calca Mutation: |
21 strains or lines available
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Original: |
J:190366 Song H, et al., Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17531-6 |
All: |
21 reference(s) |
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