Neurod2tm1Tap
Targeted Allele Detail
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Symbol: |
Neurod2tm1Tap |
Name: |
neurogenic differentiation 2; targeted mutation 1, Steven J Tapscott |
MGI ID: |
MGI:2385828 |
Gene: |
Neurod2 Location: Chr11:98216241-98220471 bp, - strand Genetic Position: Chr11, 61.75 cM
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Alliance: |
Neurod2tm1Tap page
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Germline Transmission: |
Earliest citation of germline transmission:
J:69606
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The entire coding region of the gene was replaced with an in-frame lacZ gene followed by a loxP flanked neomycin selection cassette. The neomycin selection cassette was removed in ES cells by transient Cre expression prior to the production of chimeric mice. Northern blot analysis on RNA derived from brain of homozygous mice demonstrated that no detectable transcript was expressed from this allele.
(J:69606)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Neurod2 Mutation: |
23 strains or lines available
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Original: |
J:69606 Olson JM, et al., NeuroD2 is necessary for development and survival of central nervous system neurons. Dev Biol. 2001 Jun 1;234(1):174-87 |
All: |
11 reference(s) |
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