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Chemically induced Allele Detail
Symbol: Zeb1m1Btlr
Name: zinc finger E-box binding homeobox 1; mutation 1, Bruce Beutler
MGI ID: MGI:5428990
Synonyms: cellophane
Gene: Zeb1  Location: Chr18:5591860-5775467 bp, + strand  Genetic Position: Chr18, 4.42 cM
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
Mutation detailsENU-induced a T to A transversion at position 2725 in exon 7 of 8 exons. This mutation results in the conversion of a tyrosine codon at position 902 to a premature stop codon. (J:185495)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Zeb1 Mutation:  15 strains or lines available
Original:  J:185495 Arnold CN, et al., A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12286-93
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory