Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Asltm1.1Brle
Name:	argininosuccinate lyase; targeted mutation 1.1, Brendan Lee
MGI ID:	MGI:5308971
Synonyms:	Aslflox
Gene:	Asl  Location: Chr5:130040099-130053222 bp, - strand  Genetic Position: Chr5, 68.37 cM
Alliance:	Asltm1.1Brle page

Germline Transmission:	Earliest citation of germline transmission: J:180208
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     Flp-mediated recombination remvoed the neo cassette and left exons 7 through 9 floxed. (J:180208)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Asl Mutation:	24 strains or lines available

Original:	J:180208 Erez A, et al., Requirement of argininosuccinate lyase for systemic nitric oxide production. Nat Med. 2011 Dec;17(12):1619-26
All:	4 reference(s)