Ctnnb1tm3Kba
Targeted Allele Detail
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Symbol: |
Ctnnb1tm3Kba |
Name: |
catenin beta 1; targeted mutation 3, Konrad Basler |
MGI ID: |
MGI:5308947 |
Synonyms: |
Beta-cateninD164A-deltaC, Beta-catenindm, Ctnnb1dm |
Gene: |
Ctnnb1 Location: Chr9:120762466-120789573 bp, + strand Genetic Position: Chr9, 72.19 cM
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Alliance: |
Ctnnb1tm3Kba page
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Germline Transmission: |
Earliest citation of germline transmission:
J:178971
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Parent Cell Line: |
TC1/TC-1 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Not Specified) |
Mutations: |
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Insertion, Intragenic deletion, Single point mutation
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Mutation details: A point mutation was introduced into exon 4 resulting in a D164A mutation and a floxed hygromycin cassette was inserted via homologous recombination. In a second recombination event, a premature stop codon followed by a frameshift mutation were introduced at amino acid position 673 in exon 13 and this exon was fused to exon 15.
(J:178971)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ctnnb1 Mutation: |
49 strains or lines available
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Original: |
J:178971 Valenta T, et al., Probing transcription-specific outputs of beta-catenin in vivo. Genes Dev. 2011 Dec 15;25(24):2631-43 |
All: |
13 reference(s) |
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