Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Igktm1Ktom
Name:	immunoglobulin kappa chain complex; targeted mutation 1, Kazuma Tomizuka
MGI ID:	MGI:5305476
Synonyms:	deltakappa-
Gene:	Igk  Location: Chr6:67532620-70703738 bp, + strand  Genetic Position: Chr6, 30.89 cM, cytoband F1-pter

Germline Transmission:	Earliest citation of germline transmission: J:59894
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A neo cassette replaced a 2 kb segment containing the Ckappa exon. (J:59894)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igk Mutation:	25 strains or lines available

Original:	J:59894 Tomizuka K, et al., Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies. Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):722-7
All:	1 reference(s)