Tg(UPII-SV40T)9Xrw Transgene Detail MGI Mouse (MGI:2384609)

Tg(UPII-SV40T)9Xrw
Transgene Detail

Summary

Symbol:	Tg(UPII-SV40T)9Xrw
Name:	transgene insertion 9, Xue-Ru Wu
MGI ID:	MGI:2384609
Synonyms:	UPII-SV40T
Transgene:	Tg(UPII-SV40T)9Xrw Location: unknown
Alliance:	Tg(UPII-SV40T)9Xrw page

Transgene
origin

Strain of Origin:

FVB/N

Transgene
description

Transgene Type:		Transgenic (Inserted expressed sequence)
Mutation:		Insertion
		Mutation details: This transgene contains the mouse Upk2 (uroplakin 2) promoter and the wild-type allele of the SV40 large T antigen (TAg) gene. The founder mouse carried 2 copies of the transgene. (J:56305)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Tumor Data

List all tumor models in MMHCdb carrying Tg(UPII-SV40T)9Xrw

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

This line carries 2 copies of the transgene. Three other lines were produced: line 2 with 10 copies of the transgene, line 19 with 2 copies, and line 29, which has 6 copies.

References

Original:	J:56305 Zhang ZT, et al., Urothelium-specific expression of an oncogene in transgenic mice induced the formation of carcinoma in situ and invasive transitional cell carcinoma. Cancer Res. 1999 Jul 15;59(14):3512-7
All:	3 reference(s)

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