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Tbptm1Ees
Targeted Allele Detail
Summary
Symbol: Tbptm1Ees
Name: TATA box binding protein; targeted mutation 1, Edward E Schmidt
MGI ID: MGI:2183358
Gene: Tbp  Location: Chr17:15720150-15737689 bp, + strand  Genetic Position: Chr17, 8.95 cM
Alliance: Tbptm1Ees page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77714
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation detailsThe majority of exon 3 was replaced with 2 tandem copies of the FLAG epitope tag and a loxP-flanked MC1-neo cassette was inserted 2.5 kb upstream of the promoter via homologous recombination. (J:77714)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbp Mutation:  10 strains or lines available
References
Original:  J:77714 Hobbs NK, et al., Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental beta2m-Dependent Interactions with the Maternal Immune System. Cell. 2002 Jul 12;110(1):43-54
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory