Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mapttm3(Sema3e)Arbr
Name:	microtubule-associated protein tau; targeted mutation 3, Silvia Arber
MGI ID:	MGI:3848811
Synonyms:	TauSema3
Gene:	Mapt  Location: Chr11:104122216-104222916 bp, + strand  Genetic Position: Chr11, 67.79 cM, cytoband E1
Alliance:	Mapttm3(Sema3e)Arbr page

Germline Transmission:	Earliest citation of germline transmission: J:149553
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A cassette containing a floxed STOP, Sema3e coding sequence, IRES, lacZ gene with a nuclear localization signal, and neo cassette was inserted into exon 2. Expression of Sema3e is only achieved following cre mediated recombination. (J:149553)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapt Mutation:	428 strains or lines available

Original:	J:149553 Pecho-Vrieseling E, et al., Specificity of sensory-motor connections encoded by Sema3e-Plxnd1 recognition. Nature. 2009 Jun 11;459(7248):842-6
All:	1 reference(s)