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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mapttm3(Sema3e)Arbr
targeted mutation 3, Silvia Arber
MGI:3848811
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Chattm2(cre)Lowl/Chat+
Mapttm3(Sema3e)Arbr/Mapttm3(Sema3e)Arbr 		involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 MGI:3848833


Genotype
MGI:3848833
cn1
Allelic
Composition		 Chattm2(cre)Lowl/Chat+
Mapttm3(Sema3e)Arbr/Mapttm3(Sema3e)Arbr
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chattm2(cre)Lowl mutation (4 available); any Chat mutation (57 available)
Mapttm3(Sema3e)Arbr mutation (0 available); any Mapt mutation (428 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal motor neuron innervation pattern ( J:149553 )
• 23% of triceps motor neurons receive monosynaptic input from triceps afferents compared to 95% in wild-type mice
• however, triceps and cutaneous maximus motor neurons normally lack monosynaptic input from cutaneous maximus afferents

behavior/neurological
behavior/neurological phenotype ( J:149553 )
N
• mice exhibit no behavior deficits




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory