Summary | Mutation origin | Mutation description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sema3etm1(cre/ERT2)Arbr
Name:	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; targeted mutation 1, Silvia Arber
MGI ID:	MGI:3848810
Synonyms:	Sema3enlz
Gene:	Sema3e  Location: Chr5:14075290-14306703 bp, + strand  Genetic Position: Chr5, 5.66 cM
Alliance:	Sema3etm1(cre/ERT2)Arbr page

Germline Transmission:	Earliest citation of germline transmission: J:149553
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutations:    Insertion, Intragenic deletion   Sema3etm1(cre/ERT2)Arbr expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Sema3e (MGI:1340034)   Mutation details: The sequence downstream of the translation initiation codon was replaced with a cassette containing cre/ERT2 (ESR1), IRES, lacZ gene with a nuclear localization signal, and neo gene. The absence of transcript expression was confirmed by in situ hydridization on cervical spinal cord sections of P0 mice. (J:149553)

Activity:	Tissue activity of this recombinase allele
Driver:	Sema3e (mouse) Summary of all recombinase alleles driven by Sema3e. Alliance mouse Sema3e gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sema3e Mutation:	65 strains or lines available

Original:	J:149553 Pecho-Vrieseling E, et al., Specificity of sensory-motor connections encoded by Sema3e-Plxnd1 recognition. Nature. 2009 Jun 11;459(7248):842-6
All:	3 reference(s)