Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nlrp3m4Btlr
Name:	NLR family, pyrin domain containing 3; mutation 4, Bruce Beutler
MGI ID:	MGI:4999611
Synonyms:	ND7
Gene:	Nlrp3  Location: Chr11:59432395-59457781 bp, + strand  Genetic Position: Chr11, 37.73 cM, cytoband B1.3
Alliance:	Nlrp3m4Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU mutagenesis induced a T to C transition at 59369377 bp or position 2672 of the Nlrp3 transcript in exon 6 of 10 total exons (Genbank record NM_145827). The mutation is located in the fifth coding exon and results in a cysteine to arginine substitution at amino acid 816 (C816R). (J:171739)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nlrp3 Mutation:	61 strains or lines available

Original:	J:171739 Beutler B, Direct Data Submission 2011/05/23. MGI Direct Data Submission. 2011;
All:	1 reference(s)