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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nlrp3m4Btlr
mutation 4, Bruce Beutler
MGI:4999611
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nlrp3m4Btlr/Nlrp3m4Btlr involves: C57BL/6J MGI:4999615


Genotype
MGI:4999615
hm1
Allelic
Composition		 Nlrp3m4Btlr/Nlrp3m4Btlr
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nlrp3m4Btlr mutation (0 available); any Nlrp3 mutation (61 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased interleukin-1 beta secretion ( J:171739 )
• in macrophage from mice primed with LPS followed by nigericin treatment




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory