Abi1tm1.1Lko
Targeted Allele Detail
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| Symbol: |
Abi1tm1.1Lko |
| Name: |
abl interactor 1; targeted mutation 1.1, Leszek Kotula |
| MGI ID: |
MGI:4950557 |
| Gene: |
Abi1 Location: Chr2:22830085-22930207 bp, - strand Genetic Position: Chr2, 15.18 cM
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| Alliance: |
Abi1tm1.1Lko page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:171342
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129S/SvEv
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| Allele Type: |
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Targeted (Conditional ready, No functional change) |
| Mutation: |
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Insertion
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Mutation details: A single loxP site was inserted 5' of exon 1 and a floxed and FRT flanked neo cassette was inserted 3' of exon 1 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exon 1 floxed.
(J:171342)
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Generation of the Abi1tm1.1Lko and Abi1tm1.2Lko alleles |
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Abi1 Mutation: |
78 strains or lines available
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| Original: |
J:171342 Dubielecka PM, et al., Essential role for Abi1 in embryonic survival and WAVE2 complex integrity. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7022-7 |
| All: |
2 reference(s) |
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Analysis Tools
