Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rpe65tvrm148
Name:	retinal pigment epithelium 65; translational vision research model 148
MGI ID:	MGI:4867394
Gene:	Rpe65  Location: Chr3:159304812-159330958 bp, + strand  Genetic Position: Chr3, 82.52 cM, cytoband H4
Alliance:	Rpe65tvrm148 page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: A T-to-C point mutation results in an alteration of codon 229 from one encoding phenylalanine to serine. This codon is highly conserved in many species. (J:166679) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rpe65 Mutation:	48 strains or lines available

Original:	J:166679 Won J, et al., Mouse model resources for vision research. J Ophthalmol. 2011;2011:391384
All:	3 reference(s)