Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gpx3tm1Hjco
Name:	glutathione peroxidase 3; targeted mutation 1, Harvey J Cohen
MGI ID:	MGI:4456189
Gene:	Gpx3  Location: Chr11:54793680-54801213 bp, + strand  Genetic Position: Chr11, 32.13 cM, cytoband B3-B5
Alliance:	Gpx3tm1Hjco page

Germline Transmission:	Earliest citation of germline transmission: J:159745
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neo cassette replaced the 3' portion of exon 2 through exon 5. The absence of protein was confirmed by immunohistochemistry on kidney samples. (J:159745)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gpx3 Mutation:	36 strains or lines available

Original:	J:159745 Olson GE, et al., Extracellular glutathione peroxidase (Gpx3) binds specifically to basement membranes of mouse renal cortex tubule cells. Am J Physiol Renal Physiol. 2010 May;298(5):F1244-53
All:	5 reference(s)