Analysis Tools
homeostasis/metabolism
| N |
• mice tolerate a selenium-deficient diet
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• when fed a selenium supplemented diet, plasma selenium levels are higher than in similarly treated wild-type mice
• whether fed standard chow or a selenium supplemented diet, mice exhibit reduced selenium levels in the kidney compared with similarly treated wild-type mice
• however, selenium levels in the whole body, brain, muscle, and testis are normal when mice are fed a selenium supplemented diet
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• glutathione peroxidase activity is 9% of that in wild-type mice and further decreased when mice are fed a selenium-deficient diet
• however, glutathione peroxidase activity in the kidney and liver is normal
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growth/size/body
| N |
• mice exhibit normal body weight whether fed standard chow or a selenium-deficient diet
|
renal/urinary system
| N |
• selenium excretion is normal
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