Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Grip1tm1Rlh
Name:	glutamate receptor interacting protein 1; targeted mutation 1, Richard L Huganir
MGI ID:	MGI:3798437
Synonyms:	GRIP1flox
Gene:	Grip1  Location: Chr10:119289810-119923172 bp, + strand  Genetic Position: Chr10, 67.33 cM, cytoband D2
Alliance:	Grip1tm1Rlh page

Germline Transmission:	Earliest citation of germline transmission: J:136388
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of the first coding exon and an frt-flanked neo cassette with a 3' loxP site was inserted downstream of this exon. Germ line, flp-mediated recombination was used to remove the neo cassette leaving the first coding exon floxed. (J:136388)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Grip1 Mutation:	93 strains or lines available

Original:	J:136388 Takamiya K, et al., The glutamate receptor-interacting protein family of GluR2-binding proteins is required for long-term synaptic depression expression in cerebellar Purkinje cells. J Neurosci. 2008 May 28;28(22):5752-5
All:	9 reference(s)