Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Trpm1tm1Tfur
Name:	transient receptor potential cation channel, subfamily M, member 1; targeted mutation 1, Takahisa Furukawa
MGI ID:	MGI:4421441
Gene:	Trpm1  Location: Chr7:63803583-63919523 bp, + strand  Genetic Position: Chr7, Syntenic
Alliance:	Trpm1tm1Tfur page

Germline Transmission:	Earliest citation of germline transmission: J:156502
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 4-6 were replaced with a neo cassette. Northern blot verified no substantial transcript in retinas from homozygous mice. (J:156502)

Generation of the Trpm1tm1Tfur allele

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Trpm1 Mutation:	100 strains or lines available

Original:	J:156502 Koike C, et al., TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):332-7
All:	5 reference(s)