Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Pla2g6m1J
Name:	phospholipase A2, group VI; mutation 1, Jackson
MGI ID:	MGI:4412026
Gene:	Pla2g6  Location: Chr15:79170428-79212590 bp, - strand  Genetic Position: Chr15, 37.7 cM
Alliance:	Pla2g6m1J page

Strain of Origin:

C3H/HeJ

Allele Type:    Spontaneous Mutation:    Viral insertion   Mutation details: A viral insertion occurred spontaneously in intron 1 upstream of the start codon, resulting in a dramatic reduction of transcript levels. (J:183152) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Pla2g6 Mutation:	65 strains or lines available

Original:	J:183152 Strokin M, et al., Severe disturbance in the Ca2+ signaling in astrocytes from mouse models of human infantile neuroaxonal dystrophy with mutated Pla2g6. Hum Mol Genet. 2012 Jun 15;21(12):2807-14
All:	3 reference(s)