Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Acvrl1tm2.2Spo
Name:	activin A receptor, type II-like 1; targeted mutation 2.2, S Paul Oh
MGI ID:	MGI:4398902
Synonyms:	Alk11loxP
Gene:	Acvrl1  Location: Chr15:101026403-101043217 bp, + strand  Genetic Position: Chr15, 56.41 cM, cytoband F3
Alliance:	Acvrl1tm2.2Spo page

Germline Transmission:	Earliest citation of germline transmission: J:130020
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Germ line, cre mediated recombination removed exons 4 through 6 and the neo cassette. (J:130020)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Acvrl1 Mutation:	26 strains or lines available

Original:	J:130020 Park SO, et al., ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2. Blood. 2008 Jan 15;111(2):633-42
All:	3 reference(s)