All Phenotypes Acvrl1<tm2.2Spo> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Acvrl1^tm2.2Spo
targeted mutation 2.2, S Paul Oh
MGI:4398902

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Acvrl1^tm2.2Spo/Acvrl1^tm2.2Spo	involves: 129 * C57BL/6 * FVB/N	MGI:4398917

Allelic Composition	Acvrl1^tm2.2Spo/Acvrl1^tm2.2Spo
Genetic Background	involves: 129 * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acvrl1^tm2.2Spo mutation (0 available); any Acvrl1 mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• mice die at E10.5

embryo

absent vitelline blood vessels ( J:130020 )

• at E9.5

embryonic growth retardation ( J:130020 )

• at E9.5

cardiovascular system

absent vitelline blood vessels ( J:130020 )

• at E9.5

hemorrhage ( J:130020 )

• at E9.5, mice exhibit blood pooling in the head and tail regions unlike wild-type mice

growth/size/body

embryonic growth retardation ( J:130020 )

• at E9.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24